Timeline of scientific instruments including telescope, microscope, spectroscope, Geiger counter, electron microscope, and advanced quantum computing tools.
A detailed timeline illustrating key scientific instruments from 1608 to the 21st century.

The 16th century saw an explosion research and development, which we call the Scientific Revolution. That rapid development in scientific thinking I believe was due to the inspiration of the Holy Spirit in men of God — believers in Christ — who sought an understanding of God’s creation.

Isaac Newton

Isaac Newton was the brilliant physicist and mathematician who revolutionized our understanding of the universe with his laws of motion and universal gravitation as well as optics. Perhaps he was the greatest physicist who ever lived if we define that by his contribution to our understanding of the laws of physics.

Newton was an ardent believer in Jesus Christ and attended Trinity College, Cambridge, ostensibly preparing to become an Anglican minister, but staying for more than 35 years teaching, and developing his scientific theories over a few of those years but the mostly studying the Bible. His theological writings vastly outnumbered his scientific works. Newton believed in God the Father as the sole creator and Jesus Christ as His divine Son.

Michael Faraday

Michael Faraday was a chemist and physicist who established the concept of the electromagnetic field in physics. His main discoveries include the principles underlying electromagnetic induction, diamagnetism, and electrolysis. He was one of the most influential scientists in history upon whom many others who followed him built.

Physicist Ernest Rutherford said, “When we consider the magnitude and extent of his discoveries and their influence on the progress of science and of industry, there is no honour too great to pay to the memory of Faraday, one of the greatest scientific discoverers of all time.”

Michael Faraday was a devout Christian belonging to the Sandemanians, a small, strict nonconformist sect that emphasized a literal interpretation of the Bible and apostolic simplicity. He served as a deacon and twice as an elder in his congregation, maintaining a deep commitment to his faith throughout his life.

Faraday’s religious beliefs profoundly influenced his scientific work, leading him to view the universe as a divinely ordained order governed by consistent laws. He believed that the “book of nature” and the “book of God’s word” shared the same author, which fostered his conviction in the unity of forces (such as electricity and magnetism) and shaped his conceptualization of fields and lines of force. Despite this deep integration of faith and science, he explicitly rejected natural theology as a means to spiritual truth, maintaining that religious knowledge came solely from Scripture rather than scientific reasoning.

James Clerk Maxwell

James Clerk Maxwell was also one of the greatest scientists who ever lived and developed the classical theory of electromagnetic radiation. He was a devout evangelical Presbyterian who underwent a significant conversion experience in 1853 while studying at Cambridge University. He remained a committed Christian throughout his life, eventually serving as an elder in the Church of Scotland and maintaining a deep, personal relationship with the Bible.

Maxwell viewed his scientific work as a religious endeavor, believing that studying the natural world was a way to glorify God and understand the “mind of Christ.” He rejected positivism and the idea of a “God of the gaps,” arguing instead that the intelligibility and order of the universe were direct reflections of a rational Creator. His faith provided the philosophical foundation for his groundbreaking work in electromagnetism and thermodynamics, as he believed that the uniformity of natural laws stemmed from a unified divine will.

The Scientific Revolution

The evidence shows that the foundation and early leadership of the Scientific Revolution was the result of those who believed in the Christian worldview. Jesus Christ is unchanging (Hebrews 13:8) and so are His laws which define His creation. Biblical scholars held such a view like James Clerk Maxwell which motivated their search for an understanding of God’s creation.

The foundation was laid in the 16th century by notables such as Francis Bacon who has been called the father of empiricism. Following on from the 13th century scholar Roger Bacon, he was a foundational figure in the development of the scientific method.

Read Exploring the Foundations of the Scientific Revolution!

The philosophy of Archimedes, from the 3rd century BC, is defined by a rigorous integration of pure mathematics and practical engineering, where theoretical precision served to explain and harness the physical world.  He valued logical proof and geometric rigor above all, famously refusing to write treatises on mechanics because he viewed the practical applications of engineering as “ignoble and vulgar” compared to the purity of geometry. But science progressed very little after Archimedes (died c. 212 BC) until 1500 AD.

Seventeen centuries after him Francis Bacon argued that knowledge should be derived from inductive reasoning and careful observation of nature, rejecting the deductive logic of Aristotle’s Greek way of thinking that dominated his era.

Below I have collated and curated a chronological summary of the most transformative scientific discoveries and measurements of approximately the past 400 years, organized by era and field, with the scientists credited for each breakthrough. Some are theories which need observational experimental evidence.

You’ll note that the start of the modern Scientific Revolution in the 16th century through the18th century was mostly led by scientists with a Christian worldview. And most of those were biblical creationists who took seriously the historicity and scientific details of God’s creation as described in the Bible.

A Developing Trend

In the 18th century those who were not Christians seem to hold to a deist worldview still believing that the order in the universe was due to creation by an Intelligent Mind though they did not consider Him a personal God that they could know. There was a developing trend there.

In my Tables below I have written in bold text the names for all confessing Christians of any denomination (Catholic, Orthodox, Protestant, Lutheran, Evangelical etc), but not Unitarians (U), Deists (D), Quakers (Q), Mormon (M), Pantheists (P). I use normal text if they were non-believers (A for Atheists and Agnostics, J for Judaism, B for Buddhists) or their faith is not known. I denoted TE for theists who believed God used the big bang to create the universe and/or Darwinian evolution to create all species.

By the 19th century especially after Darwin published his “On the Origin of Species” (1859) a further trend away from faith in the Creator God developed.

The trend developed further after Georges Lemaitre (1927) and Edwin Hubble (1929) advanced their expanding universe hypothesis leading to what Fred Hoyle called a “big bang”. Then again after George Gamow and his graduate student Ralph Alpher developed the foundational theory of big bang nucleosynthesis through Alpher’s doctoral dissertation (1948).

In my table below I do not include these as discoveries because anything to do with the past, that is, the origin of the universe and the origin of life and evolution of plant and animal species, is not operational science but forensic speculation. I also have avoided claims that are still hotly debated one way or another.

By the 20th century there are few major discoveries made by Bible believing Christians. There are some but most scientists held/hold to Atheist, Agnostic or Deist worldviews. And several of the Christians believe in Theistic Evolution.

Over the centuries, especially after Darwin, the trend among the scientists, sampled here by major discovery, has been away from faith in Christ and the historicity of the Genesis account. Perhaps the sample is biased by the nature of those who go into science. However the decrease in the bold text names as one looks through the centuries is very obvious.


Ancient & Medieval (260 BC –1500 AD)

In the period between the year 260 BC to 1500 AD there were very few major scientific discoveries. But in the Medieval period the foundations were set by men of faith who saw the rules governing physical world as the outcome of a rational Creator.

YearDiscoveryScientist(s)
~260 BCPrinciples of levers and buoyancyArchimedes
~200 BCMeasured diameter of the EarthEratosthenes of Cyrene
~200 BCMeasured distance to the SunAristarchus of Samos
~ 700Escapement mechanism for clocksYi Xing (B)
~1267Empirical scienceRoger Bacon
~1440Movable type printing pressJohannes Gutenberg

Scientific Revolution (1500–1700)

YearDiscoveryScientist(s)
1543Heliocentric (Sun-centered)
universe
Nicolaus Copernicus
1543Modern human anatomyAndreas Vesalius
1595First compound microscopeHans Janssen &
Zacharias Janssen
1598Law of falling objectsGalileo Galilei
1600Scientific MethodFrancis Bacon
1608Refracting telescope Hans Lippershey
1609Improved refracting telescope
and showed other planets have
moons (Jupiter’s moons)
Galileo Galilei
1609Planets’ true orbits
(elliptical orbits)
Johannes Kepler
1619Analytic geometry and the
Cartesian coordinate system
René Descartes
1628Human circulatory systemWilliam Harvey
1643Air pressure with barometerEvangelista Torricelli
1653Pascal’s law (transmission
of fluid-pressure)
Blaise Pascal
1660Hooke’s law (elasticity)Robert Hooke
1662Boyle’s law (gas pressure)Robert Boyle
1665CellsRobert Hooke
1666Universal gravitationIsaac Newton
1672Accurate distance to the SunGiovanni Cassini
1678Wave theory of lightChristiaan Huygens
1680BacteriaAntonie van Leeuwenhoek
1686First biological definition
of species
John Ray
1687Laws of motionIsaac Newton

18th Century (1700–1800)

YearDiscoveryScientist(s)
1704OpticsIsaac Newton
1735Taxonomy system
(classification of life)
Carl Linnaeus
1735Marine chronometer (H1)John Harrison
1738Fluid pressure / lift
(Bernoulli’s principle)
Daniel Bernoulli
1751Lightning is electricalBenjamin Franklin (D)
1758Comets have predictable orbitsEdmond Halley (D)
1770Gulf StreamBenjamin Franklin (D)
1772NitrogenDaniel Rutherford
1774OxygenJoseph Priestley (U) &
Antoine Lavoisier
1779PhotosynthesisJan Ingenhousz
1781Uranus (expanding the
solar system)
Frederick W. Herschel
1789Law of conservation of massAntoine Lavoisier
1792Erosion and weatheringJames Hutton (TE)

19th Century (1800–1900)

YearDiscoveryScientist(s)
1800Infrared radiationFrederick W. Herschel
1800Battery (voltaic pile)Alessandro Volta
1801Ultraviolet radiationJohann Wilhelm
Ritter (D)
1801Chloroform anesthesiaJames Young Simpson
1806Electrochemical bondingHumphry Davy (D)
1808AtomsJohn Dalton
1809First electric light (arc lamp)Humphry Davy (D)
1811MoleculesAmedeo Avogadro
1814Gulf Stream mappingAlexander von Humboldt (P)
1820ElectromagnetismHans Christian
Ørsted (P)
1824Dinosaur fossilsWilliam Buckland
& Gideon Mantell
1831Electromagnetic induction, diamagnetism, and electrolysisMichael Faraday
1832Self-inductance and
electromagnetic induction
Joseph Henry
1832Earth’s magnetic fieldCarl Friedrich Gauss
(D) & Wilhelm Weber
1835Bayes’ theorem
(statistical inference)
Thomas Bayes
(published 1763)
1837Ice ageLouis Agassiz
1837Analytical Engine (computer)Charles Babbage
1843Calorie / mechanical
equivalent of heat
James Prescott Joule
1847Conservation of energyHermann von Helmholtz
1848Doppler effectChristian Doppler
1848Absolute temperature scaleLord Kelvin
(William Thomson)
18512nd law thermodynamicsLord Kelvin
(William Thomson)
1854Terrain theoryClaude Bernard (A)
& Antoine Béchamp
1855All cells arise from
pre-existing cells
Rudolf Virchow (anti-evolutionist)
1856Germ theoryLouis Pasteur
1858Natural selection
(not Darwinian evolution)
Charles Darwin (A) &
Alfred Russel Wallace
1864Theory of electromagnetismJames Clerk Maxwell
1865Laws of inheritance
(genetics)
Gregor Mendel
1865Definition of entropyRudolf Clausius
1868HeliumPierre Jules Janssen &
Norman Lockyer
1869Periodic table of elementsDmitri Mendeleev (D)
1870Deep-sea lifeCharles Wyville Thomson (TE)
1873Van der Waals forcesJohannes Diderik van der Waals
1876Chemical thermodynamicsJosiah Willard Gibbs
1877Statistical definition of
entropy
Ludwig Boltzmann (D)
1879Incandescent light bulbThomas Edison (D)
1880PiezoelectricityPierre & Jacques Curie
1880Modern seismographJohn Milne
1882Cell division (mitosis)Walther Flemming
1887Michelson-Morley
experiment (no aether)
Albert A. Michelson (A)
& Edward Morley
1887Polyphase A.C. power supplyNikola Tesla (P)
1887AC induction motorNikola Tesla (P)
1890Maunder Minimum
(sunspots)
Edward Walter Maunder
1892VirusesDmitri Ivanovsky
1895X-raysWilhelm Conrad Röntgen
1895Wireless telegraphy (radio)Guglielmo Marconi
1896RadioactivityHenri Becquerel
1897ElectronJ.J. Thomson
1898Telegraphone (magnetic
recording device)
Valdemar Poulsen
1898Virus as distinct entityMartinus Beijerinck
1898HormonesJohn Abel, William
Bayliss & Ernest Starling
1898MitochondriaCarl Benda

20th Century (1900–2000)

YearDiscoveryScientist(s)
1900Quantum theoryMax Planck (D)
1901Radioactivity (systematic study)Marie (A) & Pierre Curie (A)
1901ABO blood groupsKarl Landsteiner
1902Atmospheric layersLéon Teisserenc de Bort
1902Statistical mechanicsLudwig Boltzmann (D),
James Clerk Maxwell
& Josiah Willard Gibbs
1904ArgonWilliam Ramsay & Lord Rayleigh (John William Strutt)
1905Special relativity / E=mc²Albert Einstein (D)
1905Photoelectric effect (dual nature of photons)Albert Einstein (D)
1905Explained Brownian motionAlbert Einstein (D)
1907Radioactive datingBertram Boltwood
1908Geiger counterHans Geiger
1909Genetic mutations / gene-chromosome mappingThomas Hunt Morgan (A)
1911Atomic nucleus (Rutherford model)Ernest Rutherford (A)
1911SuperconductivityHeike Kamerlingh Onnes
1912Cosmic raysVictor Hess
1912Continental driftAlfred Wegener
1913Atomic model (Bohr model)Niels Bohr (A)
1913IsotopesFrederick Soddy (A)
1914NeurotransmittersHenry Dale & Otto Loewi
1915General theory of relativityAlbert Einstein (D)
1916Black holes (theoretical)Karl Schwarzschild
1920ProtonErnest Rutherford (A)
1921Insulin isolationFrederick Banting
& Charles Best
1923Nature of galaxiesEdwin Hubble (A)
1925Quantum mechanics (matrix/wave formulations)Werner Heisenberg
& Erwin Schrödinger (D)
1925Pauli exclusion principleWolfgang Pauli (D)
1926Wave mechanics (Schrödinger equation)Erwin Schrödinger (D)
1926Liquid-fueled rocketRobert H. Goddard
1927Uncertainty principleWerner Heisenberg
1927First quartz clockWarren Marrison
& J.W. Horton
1927Electronic television (TV)Philo Farnsworth (M)
1928PenicillinAlexander Fleming
1929AntimatterPaul Dirac (A)
1929Redshifts and Hubble’s lawEdwin Hubble (A)
& Milton Humason
1930Strong nuclear forceErnest Rutherford (A)
1931Radio astronomyKarl Jansky
1932NeutronJames Chadwick (A)
1933Cell structure (electron microscopy)Albert Claude
1933Beta decay (theory)Enrico Fermi (A)
1934Induced radioactivityEnrico Fermi (A)
1934Genes control metabolismGeorge Beadle (A)
& Edward Tatum
1937Strong nuclear force (theory)Hideki Yukawa (B)
1938Earth’s solid inner coreInge Lehmann
1938Metabolism / Krebs cycleHans Krebs
1939Nuclear fissionLise Meitner & Otto Hahn
1939Nuclear fusion (stellar energy source)Hans Bethe
1939Blood plasma storageCharles Richard Drew
1942First nuclear reactorEnrico Fermi (A)
1944First man-made object (rocket) to reach spaceWernher von Braun
1945First electronic computer (ENIAC)John Mauchly & J. Presper Eckert
1946Stellar nuclear synthesisFred Hoyle (A)
1947Semiconductor transistorJohn Bardeen, Walter
Brattain & William Shockley
1947 Pion discovered (confirmed Yukawa theory)Hideki Yukawa (B)
1948 First atomic clock (ammonia molecules)Harold Lyons
1948Instant photography (Polaroid Land Camera)Edwin H. Land 
1949Radiocarbon dating methodWillard Libby
1950Jumping genes (transposons)Barbara McClintock (A)
1951Nuclear fusion (stellar processes)Lyman Spitzer
1953Structure of DNAJames Watson (A), Francis Crick (A) & Rosalind Franklin (A)
1955First accurate atomic clock (caesium-133 beam)Louis Essen & Jack Parry
1957Seafloor spreadingHarry Hess
1959Gravitational redshiftRobert Pound & Glen Rebka
1960First working laserTheodore Maiman
1963QuasarsAllan Sandage (TE)
& Maarten Schmidt (A)
1964Cosmic microwave background radiationArno Penzias (TE) & Robert Wilson (TE)
1967PulsarsJocelyn Bell Burnell (Q) & Antony Hewish
1969Apollo 11 Moon landingNeil Armstrong
& Buzz Aldrin
1969Magnetic Resonance Imaging (MRI)Raymond Damadian
1971Black holes (modern concept)John Archibald Wheeler (U)
1971Computed tomography (CT) scannerGodfrey Newbold Hounsfield
1983Weak nuclear force carriersCarlo Rubbia
1995Exoplanets (planets around other stars)Michel Mayor (A)
& Didier Queloz (A)

21st Century (2000–2015)

YearDiscoveryScientist(s)
2003Human Genome Project completedCraig Venter (A) & James Watson (A)/ international consortium
2005Dinosaur soft tissueMary Schweitzer (TE)
2012Higgs bosonCERN / ATLAS & CMS collaborations, Peter Higgs (A)
2012CRISPR-Cas9 gene editingJennifer Doudna & Emmanuelle Charpentier
2015Gravitational wavesLIGO collaboration (Barry Barish, Kip Thorne (A), Rainer Weiss (J))

Forgive me if I have not included some significant scientific discovery or development. If so, let me know in the Comments and I can include it.

Brief Summary by Field

Astronomy & Physics: Heliocentrism (Copernicus), gravity (Newton), electromagnetism (Maxwell), relativity (Einstein), quantum mechanics (Planck, Heisenberg, Schrödinger), redshift / galaxies (Hubble, Humason), black holes (Schwarzschild, Wheeler), gravitational waves (LIGO), and the Higgs boson (CERN).

Chemistry & Matter: Conservation of mass (Lavoisier), atoms (Dalton), periodic table (Mendeleev), radioactivity (Curie), nuclear fission (Meitner/Hahn), DNA structure (Watson/Crick/Franklin).

Biology & Medicine: Cells (Hooke), germ theory (Pasteur), natural selection (Darwin/Wallace), genetics (Mendel), penicillin (Fleming), insulin (Banting/Best), the human genome (Venter/Watson), and CRISPR (Doudna/Charpentier).

Earth & Environment: Earth’s solid inner core (Inge Lehmann), continental drift (Wegener), seafloor spreading (Hess), and an Ice age (Agassiz).


These many discoveries represent the pillars upon which modern science, medicine, and technology rest. In the later centuries many have been the result of collaborative teamwork rather than lone geniuses, reflecting how science has developed from individual insight in the 16th century to large-scale international effort in the 21st century

But it was those individual insights inspired by the Holy Spirit in the minds of Christian men of God that started this revolution in science approximately 400 years ago. Let’s not lose sight of that.


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